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ADHD Medications

Comprehensive guide to stimulant and non-stimulant options for managing ADHD in children and adults, helping you find focus and reach your potential.

Key Fact:ADHD medications help the brain's focus centers work more effectively without changing who you are.
Dr. Bessy Martirosyan
Written by
Dr. Bessy Martirosyan
Kevin Hamilton, PMHNP
Reviewed by
Kevin Hamilton, PMHNP
8.7%
Children with ADHD
4.4%
Adults with ADHD
70-80%
Respond to medication
Multiple
Treatment options available
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Understanding ADHD Medications


ADHD medications work by improving the way certain brain chemicals (neurotransmitters) function, particularly dopamine and norepinephrine. These medications don't cure ADHD but can significantly improve focus, impulse control, and hyperactivity.

What ADHD Medications Can Help With:
  • ✓ Improved focus and concentration
  • ✓ Better impulse control
  • ✓ Reduced hyperactivity
  • ✓ Enhanced organization skills
  • ✓ Better academic/work performance
  • ✓ Improved emotional regulation
  • ✓ Reduced risk-taking behaviors

How ADHD Medications Work

The ADHD Brain

ADHD brains have differences in dopamine and norepinephrine activity. These neurotransmitters are crucial for:

  • Dopamine: Motivation, reward, and attention
  • Norepinephrine: Alertness, arousal, and attention

ADHD medications help these neurotransmitters work more effectively, improving brain communication in areas responsible for executive function.

Medication Response Timeline

Stimulants: 30-60 minutes

Fast-acting, effects noticeable quickly. Full benefits within 1-2 hours.

Non-Stimulants: 2-4 weeks

Gradual improvement over time. Full benefits may take 6-8 weeks.

Stimulant Medications

Stimulants are the most commonly prescribed and typically most effective ADHD medications. Despite the name, they have a calming, focusing effect on people with ADHD.

Medication TypeBrand NamesDurationKey Features
Methylphenidate (Short-Acting)Ritalin, Methylin3-4 hoursQuick onset, flexible dosing
Methylphenidate (Long-Acting)Concerta, Ritalin LA, Quillivant8-12 hoursOnce daily, steady levels
Amphetamine (Short-Acting)Adderall, Dexedrine4-6 hoursPotent, quick acting
Amphetamine (Long-Acting)Adderall XR, Vyvanse10-14 hoursAll-day coverage

Advantages of Stimulants

  • Fast-acting (30-60 minutes)
  • 70-80% response rate
  • Decades of safety data
  • Multiple formulations available
  • Can adjust dose quickly

Considerations

  • Controlled substances (DEA Schedule II)
  • Monthly prescriptions often required
  • Potential for misuse
  • May affect sleep if taken late
  • Regular monitoring needed

Non-Stimulant Medications

Non-stimulants are alternatives for those who can't take or don't respond well to stimulants. They work differently and may have fewer side effects for some people.

Atomoxetine (Strattera)

Selective norepinephrine reuptake inhibitor
  • Once or twice daily dosing
  • Not a controlled substance
  • Takes 2-4 weeks to work
  • 24-hour symptom control
  • Good for anxiety comorbidity

Alpha-2 Agonists

Guanfacine (Intuniv) & Clonidine (Kapvay)
  • Originally blood pressure meds
  • Help with hyperactivity/impulsivity
  • Can be used alone or with stimulants
  • May help with sleep
  • Good for tics/Tourette's

Bupropion (Wellbutrin)

Off-label use for ADHD
  • Antidepressant with ADHD benefits
  • Good for ADHD + depression
  • Not controlled substance
  • Less effective than stimulants
  • May help with smoking cessation

Choosing the Right Medication

Factors to Consider:

  • Symptom profile: Inattentive vs. hyperactive vs. combined
  • Duration needed: School/work hours vs. all day
  • Side effect tolerance: Sleep, appetite, mood
  • Comorbid conditions: Anxiety, depression, tics
  • Substance use history: Personal or family
  • Cardiovascular health: Heart conditions
  • Convenience: Once vs. multiple daily doses
  • Cost/insurance: Coverage varies

When to Consider Non-Stimulants:

  • ✓ History of substance use disorder
  • ✓ Significant anxiety
  • ✓ Tics or Tourette syndrome
  • ✓ Sleep problems
  • ✓ Cardiovascular concerns
  • ✓ Poor response to stimulants
  • ✓ Intolerable stimulant side effects

ADHD Medications for Children

Age Considerations

Ages 4-5

Behavior therapy first. Medication if severe symptoms and therapy insufficient.

Ages 6+

Medication + behavior therapy recommended as first-line treatment.

Starting Treatment

  • Start with lowest dose
  • Gradual increases weekly
  • Monitor growth and development
  • Regular check-ins with teacher
  • Track sleep and appetite

School Considerations

  • Timing doses for school hours
  • Medication breaks (weekends/summer)
  • Communication with school nurse
  • Academic accommodations
  • Behavioral interventions

Parent Tips

  • Keep medication log
  • Use reminder systems
  • Monitor for side effects
  • Maintain routines
  • Celebrate improvements

ADHD Medications for Adults

Adult-Specific Considerations:

  • Work schedule flexibility
  • Driving requirements
  • Pregnancy/breastfeeding plans
  • Interaction with other medications
  • Cardiovascular risk factors
  • Substance use screening

Benefits Often Seen in Adults:

  • ✓ Improved work performance
  • ✓ Better relationship stability
  • ✓ Reduced driving accidents
  • ✓ Better financial management
  • ✓ Improved parenting
  • ✓ Reduced risk of substance use

Managing Side Effects

Many side effects are manageable with dose adjustments, timing changes, or switching formulations. Below are common issues and practical tips.

Common Stimulant Side Effects

  • Appetite loss: Offer larger meals earlier in the day; consider caloric snacks when appetite returns.
  • Sleep difficulty: Move doses earlier, consider shorter-acting formulations, and practice good sleep hygiene.
  • Irritability/mood changes: Monitor closely; dose timing or lowering dose often helps.
  • Increased heart rate/blood pressure: Usually mild; inform your provider if you have cardiovascular risk.

Non-Stimulant Side Effects

  • Gastrointestinal upset: Often improves over time; take with food if needed.
  • Sleepiness or fatigue: Common with alpha-2 agonists; dosing at bedtime can help.
  • Mood/activation changes: Report any new mood symptoms promptly to your provider.

When to Contact Your Provider

  • Severe chest pain or shortness of breath: Seek urgent care.
  • Suicidal thoughts or severe mood changes: Contact your provider immediately or go to the emergency room.
  • Marked weight loss or growth concerns (children): Your provider may adjust dosing or treatment.

Frequently Asked Questions

Find Your Focus

Our ADHD specialists will help you find the right treatment approach for your unique needs.

Important Medical Disclaimer
This information is for educational purposes only. ADHD medications require proper diagnosis and medical supervision. Never start, stop, or change medication without consulting your healthcare provider. Stimulant medications are controlled substances and must be used exactly as prescribed.